MCC(microcrystalline cellulosepellets are made of only microcrystalline cellulose (MCC). As critical pharmaceutic adjuvant, MCC pellets are used as cores to be coated in the manufacture of controlled-release or sustained-release formulations. It enables greater accuracy and consistency in drug layering and coating.
Appearance : White or kind of white near circular pellets.
Application: As critical pharmaceutic sugar-free core for the manufacture of sustained & controlled-release pellets.
MCC 100% & Purified water;
Polymerization: not more than 350;
Water: Between 4.0% and 5.5%;
Bulk density: About 0.80 g/cm3 ± 5%;
Conductivity: less than 75µS/cm;
PH: Between 5.0 and 7.5;
Dissolved in ether: residue is not more than 0.05%;
Dissolved in water: residue is not more than 0.25%;
Heavy metal: not more than 10ppm;
Residue on ignition: not more than 0.1%;
Loss of drying: weight loss is not more than 6%;
Aerobic bacteria is not more than 1000 cuf per g
Moulds and yeasts is not more than 100 cuf per g
2.High physico-chemical stability, so it is of benefit to the stability of finished products;
3.High hardness and low friability;
4.Insoluble in water and organic solvent, low osmotic pressure;
5.Porous structure promote to absorb more active component;
MCC pellets( 0.71-1.0mm) in the microscope (40 multiple)
Storage:Preserve in tight containers,keep it in dry place